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- _4 wasQuotedFrom 10640277 provenance.
- _4 value "An up-regulation of Mash1 (Ascl1) expression was observed throughout the dorsomedial cortical ventral zone of Ngn2 mutant embryos at E12.5 and E13.5. This up-regulation was less apparent in the lateral ventral zone in which Ngn1 expression was maintained in Ngn2 mutants. Mash1 up-regulation was strikingly enhanced in the dorsal telencephalon and dorsal thalamus of Ngn1 and Ngn2 double mutant embryos. These results suggest that the Ngns function in a partially redundant manner to restrict Mash1 expression to limited domains of the forebrain neuroepithelium." provenance.