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- _3 wasQuotedFrom 10490822 provenance.
- _3 value "We injected a monoclonal antibody directed against the SH3 domain of Ras-GAP (mAb200) that has been shown to block Ras-GAP downstream signalling into various human normal and tumour cell lines. When mAb200 was microinjected into lung carcinoma H460 cells, cervix carcinoma HeLa cells and colon carcinoma HCT116 cells, massive cell death occurred. Breast carcinoma SKBR3 cells, non small lung H322 and colon HT29 carcinoma cells were also sensitive to the mAb200 antibody, although to a lesser extent (data not shown)." provenance.