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- _5 wasQuotedFrom 10517677 provenance.
- _5 value "3-phosphoinositide-dependent protein kinase-1 (PDK-1) is required for activation of atypical PKCs. Overexpression of wild-type PDK-1 provoked increases in the activity of cotransfected hemagglutinin (HA)-tagged PKC-zeta and concomitantly enhanced HA-tagged GLUT4 translocation... Thr-410, the immediate target of PDK-1 in the activation loop of PKC-zeta" provenance.