Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAouNcbNePg0wSkF5vPHcsx55WWMBuZ6tl-UZxgBQf5V0#_4> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _4 wasQuotedFrom 19508391 provenance.
- _4 value "Further, LPS + IFNγ -induced expression of iNOS and Nox1 was attenuated by the mitogen-activated protein kinase kinase 1/2 (MEK1/2) inhibitor PD98059, the JNK inhibitor SP600125, the Jak2 inhibitor AG490 and the NFκB inhibitor MG132, but not by the p38 mitogen-activated protein kinase inhibitor SB203580. LPS + IFNγ stimulated phosphorylation of ERK, JNK and Jak2, and degradation of IκB, but only Jak2 phosphorylation was sensitive to tripterine (50-200 nM). Further, tripterine diminished the increased vascular permeability in inflamed air pouches." provenance.