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- _6 value "When the cells were exposed to 500 uM H2O2, enzymatic activation of caspase-3 and -8 was significantly increased in wt BEAS-2B cells in a time dependent manner (Figures 2e and f: closed circles). Moreover, the activities were higher in Prdx6KD than in wt BEAS-2B cells (Figures 2e and f: open circles)." provenance.