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- _4 wasQuotedFrom 15916985 provenance.
- _4 value "Resistin appears to be an important regulator of glucose homeostasis, adipogenesis, and, potentially, inflammation [65, 66]. Obesity induced by a high fat diet, mutation of the leptin gene (ob-/ob- mice), or the leptin receptor gene (db-/db- mice) is associated with increased circulating resistin concentrations [50]. Resistin induces insulin resistance in mice and regulates the deposition of adipose tissue through a negative feedback mechanism." provenance.