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- _4 wasQuotedFrom 12444029 provenance.
- _4 value "however, after stimulation with interleukin-1beta or tumor necrosis factor-alpha, levels of ESE-3 mRNA and protein increase dramatically by 24 h. ESE-3 mRNA and Protein Are Inducibly Expressed in Human Bronchial Smooth Muscle Cells after Treatment with TNF-{alpha} or IL-1beta To test the hypothesis that ESE-3 may be induced in other cells of the airways in response to inflammatory cytokines of relevance to asthma, we exposed HBSMC to TNF-{alpha} and IL-1beta. ESE-3 mRNA was induced 6 to 24 h after treatment with both cytokines, each at a concentration of 5 ng/ml, and detected by RT-PCR" provenance.