Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAw3U-BO_NMxA3Tya3Z4cG4Pzti98i8yn_XY8bRw7P95I#_4> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _4 wasQuotedFrom 15014502 provenance.
- _4 value "Here we show that both Skp2 and Cks1 proteins are unstable in G1 and that their degradation is mediated by the ubiquitin ligase APC/C(Cdh1) (anaphase-promoting complex/cyclosome and its activator Cdh1). Silencing of Cdh1 by RNA interference in G1 cells stabilizes Skp2 and Cks1, with a consequent increase in p21 and p27 proteolysis." provenance.