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- _5 wasQuotedFrom 15064416 provenance.
- _5 value "MRN stimulates the kinase activity of ATM in vitro toward its substrates p53, Chk2, and histone H2AX. MRN makes multiple contacts with ATM and appears to stimulate ATM activity by facilitating the stable binding of substrates .. phospho-sites from Figs 1-2" provenance.