Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAxud5qoMzSLbBRPnMWO7vPr2vLtFgNnPN9rn-eDPd19U#_2> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _2 wasQuotedFrom 12764228 provenance.
- _2 value "Skeletal muscle contains myofibers that differ greatly in their oxidative capacity. Prolonged electrical stimulation or exercise training can lead to a conversion of type II (fast-twitch) muscle fibers to type I (slow-twitch) fibers (1). This conversion is characterized by dramatic changes in the expression of a large number of genes that increase mitochondrial biogenesis, oxidative capacity, and amounts of a distinct set of contractile proteins characteristic of this fiber type (2). Several key factors in this signaling cascade have been identified recently. Exercise training is accompanied by an increase in motor nerve activity that subsequently elevates intracellular calcium levels in the muscle (3, 4)." provenance.