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- _6 wasQuotedFrom 11841347 provenance.
- _6 value " However, the functions of uPA are not limited to the proteolytic activation of plasmin and of the growth factors on the cell surface. Recently accumulated data suggest that binding of uPA to membrane receptors on certain cells also directly initiates signaling cascades involved in the regulation of cell migration and proliferation independently of the ability of uPA to activate the growth factors. Thus, uPA-induced cell migration is associated with the activation of Janus kinases and of nonreceptor Src-kinases in certain cells [47-49]." provenance.