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- _5 wasQuotedFrom 15602009 provenance.
- _5 value "Pro-TNF-{alpha} is finally converted to active TNF-{alpha} by a membrane-bound metalloproteinase called TNF-{alpha} converting enzyme (TACE), although other matrix metalloproteinases also have a greater or lesser degree of TNF-{alpha} converting potential (Gearing et al., 1994Go). In vitro MMP-12 also releases active TNF-{alpha} from a synthetic pro-form," provenance.