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- _5 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- _3 title "Biochemistry of Lipids, Lipoproteins and Membranes 2002 - Chapter 5" provenance.
- _3 type "Book" provenance.
- _3 identifier "Biochemistry of Lipids, Lipoproteins and Membranes 2002 - Chapter 5" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "1.4" provenance.
- large_corpus.bel authoredBy _5 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _4 provenance.
- assertion hadPrimarySource _3 provenance.
- _4 wasQuotedFrom _3 provenance.
- _4 value "the cellular concentration of malonyl-CoA is directly related to the activity of acetyl-CoA carboxylase the short-term regulation of acetyl-CoA carboxylase involves the phosphorylation and dephosphorylation of the enzyme in the fasting animal, a high [glucagon]/[insulin] ratio causes the phosphorylation and inactivation of acetyl-CoA carboxylase as a consequence, the concentration of malonyl-CoA and the rate of fatty acid synthesis decrease, while the rate of beta-oxidation increases a decrease of the [glucagon]/[insulin] ratio reverses these effects thus, both fatty acid synthesis and fatty acid oxidation are regulated by the ratio of [glucagon]/[insulin]" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.