Matches in Nanopublications for { ?s ?p ?o <http://www.tkuhn.ch/bel2nanopub/RAqxCNCvzf72LJW2yDvtMaX5kkPOWi3uKgR1J8DWYVQ0Q#provenance>. }
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- _7 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _7 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _6 provenance.
- assertion hadPrimarySource 15917250 provenance.
- _6 wasQuotedFrom 15917250 provenance.
- _6 value "Activated Yes rapidly associates with the EGFR and triggers its phosphorylation at tyrosine residues Tyr845 and Tyr1173. EGFRTyr845 is a known Src target (52), whereas Tyr1173 reflects an activating autophosphorylation site of the EGFR (53). Yes inhibition by SU6656 abolishes EGFR phosphorylation at both sites, whereas AG1478 inhibits EGFR-Tyr1173 phosphorylationbut not phosphorylation at Tyr845. These findings suggest that Yes activates the EGFR at Tyr845, which is followed by activating autophosphorylation at Tyr1173." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.